BCMA (TNFRSF17) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc Tag |
| Predicted MW | The protein has a predicted molecular mass of 32.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Bioactivity | EC50=3.163 |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 608 |
| UniProt ID | Q02223 |
| Synonyms | TNFRSF17;CD269;BCM;BCMA |
| Summary | B-cell maturation protein (BCMA or BCM), is also known as Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), which is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). This receptor is expressed in immune organs and mature B cell lines. BCMA promotes B-cell survival and plays a role in the regulation of humoral immunity. BCMA can activate NF-kappa-B and JNK. |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA |
| Protein Pathways | Cytokine-cytokine receptor interaction |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "BCMA" proteins (10)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC400483 | Lyophilized BCMA/TNFRSF17 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400483 | Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17) (as WB positive control) | 100 ug |
$436.00
|
|
| TP700293 | Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), with C-terminal Fc tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP721282 | Human BCMA Protein (C-Fc) | 25 ug |
$300.00
|
|
| TP721283 | Human BCMA Protein (C-Fc-Avi) | 25 ug |
$300.00
|
|
| TP721284 | Biotinylated Human BCMA Protein (C-Fc-Avi) | 25 ug |
$430.00
|
|
| TP721285 | PE Conjugated Human BCMA Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP721286 | APC Conjugated Human BCMA Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP723924 | Recombinant human BCMA protein with C-terminal human Fc and 6×His tag | 100 ug |
$795.00
|
|
| TP762590 | Purified recombinant protein of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), full length, with N-terminal GST and C-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$270.00
|
|
Citations
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