BCMA (TNFRSF17) (NM_001192) Human Recombinant Protein

SKU
TP700293
Purified recombinant protein of human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), with C-terminal Fc tag, expressed in human cells, 20 µg
  $900.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC208851, encoding the region (Met1 – Ala54) of human TNFRSF17
Tag C-Fc
Predicted MW 33 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001183
Locus ID 608
UniProt ID Q02223
Cytogenetics 16p13.13
RefSeq Size 994
RefSeq ORF 552
Synonyms BCM; BCMA; CD269; TNFRSF13A
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. provided by RefSeq, Jul 2008
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction
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