Mesothelin (MSLN) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 59.3 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 10232 |
| UniProt ID | Q13421 |
| Synonyms | MSLN;Mesothelin;MPF |
| Summary | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Protein Categories | ADC Targets, CAR-T Targets, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Mesothelin" proteins (21)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH302532 | MSLN MS Standard C13 and N15-labeled recombinant protein (NP_005814) | 10 ug |
$3,360.00
|
|
| LC401768 | Lyophilized MSLN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC415604 | Lyophilized MSLN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC429380 | Lyophilized MSLN HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY401768 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY415604 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY429380 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| TP302532 | Recombinant protein of human mesothelin (MSLN), transcript variant 1, 20 µg | 20 ug |
$737.00
|
|
| TP721264 | Human Mesothelin (R35-E298) Protein (C-His) | 25 ug |
$300.00
|
|
| TP721265 | Human Mesothelin (E296-G580) Protein (C-His) | 25 ug |
$300.00
|
|
| TP721266 | Human Mesothelin (E296-G580) Protein (C-His-Avi) | 25 ug |
$300.00
|
|
| TP721267 | Biotinylated Human Mesothelin (E296-G580) Protein (C-His-Avi) | 25 ug |
$430.00
|
|
| TP721268 | PE Conjugated Human Mesothelin (E296-G580) Protein (C-His) | 25 ug |
$430.00
|
|
| TP721269 | APC Conjugated Human Mesothelin (E296-G580) Protein (C-His) | 25 ug |
$430.00
|
|
| TP721270 | Human Mesothelin (E296-G580) Protein (C-Fc) | 25 ug |
$300.00
|
|
| TP721271 | Human Mesothelin (E296-G580) Protein (C-Fc-Avi) | 25 ug |
$300.00
|
|
| TP721272 | Biotinylated Human Mesothelin (E296-G580) Protein (C-Fc-Avi) | 25 ug |
$430.00
|
|
| TP721273 | PE Conjugated Human Mesothelin (E296-G580) Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP721274 | APC Conjugated Human Mesothelin (E296-G580) Protein (C-Fc) | 25 ug |
$430.00
|
|
| TP723884 | Purified recombinant protein of Human mesothelin (MSLN), transcript variant 1 | 10 ug |
$245.00
|
|
| TP762350 | Purified recombinant protein of Human mesothelin (MSLN), transcript variant 2, Asn402-Thr581, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$260.00
|
|
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