Mesothelin (MSLN) (NM_013404) Human Recombinant Protein

SKU
TP762350
Purified recombinant protein of Human mesothelin (MSLN), transcript variant 2, Asn402-Thr581, with N-terminal His tag, expressed in E.coli, 50ug
  $260.00
In Stock*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence encoding the region(Asn402-Thr581) of MSLN
Tag N-His
Predicted MW 20.3 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_037536
Locus ID 10232
UniProt ID Q13421
Cytogenetics 16p13.3
RefSeq Size 2076
RefSeq ORF 1890
Synonyms MPF; SMRP
Summary This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Feb 2016
Protein Categories ADC Targets, CAR-T Targets, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, Secreted Protein, Transmembrane
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Other "Mesothelin" proteins (21)
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TP721272 Biotinylated Human Mesothelin (E296-G580) Protein (C-Fc-Avi) 25 ug
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TP721273 PE Conjugated Human Mesothelin (E296-G580) Protein (C-Fc) 25 ug
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