TIM 3 (HAVCR2) Human Recombinant Protein

SKU
TP723953
Recombinant human TIM3 protein with C-terminal mouse Fc and 6×His tag
  $825.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
TIM3(Ser22-Gly202) mFc(Pro99-Lys330) 6×His tag
Tag C-Mouse Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 84868
UniProt ID Q8TDQ0
Synonyms HAVCR2;TIM3;TIMD3;FLJ14428;KIM3
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Protein Categories CD Markers, Chemokines, Cytokines, Intracellular Proteins, Membrane Proteins
Protein Families ELISA
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Other "TIM 3" proteins (6)
SKU Description Size Price
LC403200 Lyophilized HAVCR2 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY403200 Transient overexpression lysate of hepatitis A virus cellular receptor 2 (HAVCR2) (as WB positive control) 100 ug
$436.00
TP700234 Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal DDK/His tag, expressed in human cells, 20 µg 20 ug
$900.00
TP700235 Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal Fc tag, expressed in human cells, 20 µg 20 ug
$900.00
TP720643 Purified recombinant protein of Human hepatitis A virus cellular receptor 2 (HAVCR2) 10 ug
$220.00
TP762197 Purified recombinant protein of Human hepatitis A virus cellular receptor 2 (HAVCR2), Ser22-Gly202, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$270.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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