TIM 3 (HAVCR2) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 84868 |
| UniProt ID | Q8TDQ0 |
| Synonyms | HAVCR2;TIM3;TIMD3;FLJ14428;KIM3 |
| Summary | The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
| Protein Categories | CD Markers, Chemokines, Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | ELISA |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "TIM 3" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC403200 | Lyophilized HAVCR2 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403200 | Transient overexpression lysate of hepatitis A virus cellular receptor 2 (HAVCR2) (as WB positive control) | 100 ug |
$436.00
|
|
| TP700234 | Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal DDK/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP700235 | Purified recombinant protein of human T-cell immunoglobulin mucin receptor 3 (TIM3), with C-terminal Fc tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP720643 | Purified recombinant protein of Human hepatitis A virus cellular receptor 2 (HAVCR2) | 10 ug |
$220.00
|
|
| TP762197 | Purified recombinant protein of Human hepatitis A virus cellular receptor 2 (HAVCR2), Ser22-Gly202, with N-terminal His tag, expressed in E.coli, 50ug | 50 ug |
$270.00
|
|
Citations
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