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CD40 Human Recombinant Protein

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SKU
TP723938
Recombinant human CD40 protein with C-terminal mouse Fc and 6×His tag
Size:
100 ug
  $795.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA807575 CD40 mouse monoclonal antibody, clone OTI1F12 (formerly 1F12) 100 ul
$447.00

Other products for "CD40"

Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD40(Glu21-Arg193) mFc(Pro99-Lys330) 6×His
Tag C-Mouse Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 68 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 958
UniProt ID P25942
Synonyms CD40;Bp50;CDW40;MGC9013;TNFRSF5;p50
Summary This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Protein Categories ADC Targets, CD Markers, Immune system diseases, Membrane Proteins, Secreated Proteins
Protein Families ELISA
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Viral myocarditis
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Documents
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Other "CD40" proteins (5)
SKU Description Size Price
LC400500 Lyophilized CD40 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407183 Lyophilized CD40 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400500 Transient overexpression lysate of CD40 molecule, TNF receptor superfamily member 5 (CD40), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY407183 Transient overexpression lysate of CD40 molecule, TNF receptor superfamily member 5 (CD40), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP720633 Purified recombinant protein of Human CD40 molecule, TNF receptor superfamily member 5 (CD40), transcript variant 1 10 ug
$190.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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