CD38 Human Recombinant Protein

SKU
TP723927
Recombinant human CD38 protein with C-terminal human Fc and 6×His tag
  $770.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
CD38(Val43-Ile300) hFc(Glu99-Ala330) 6×His tag
Tag C-Human Fc and 6×His Tag
Predicted MW The protein has a predicted molecular mass of 70-72 kDa after removal of the signal peptide.
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Buffer Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization
Reconstitution Method 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube.
2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000
3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL)
4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample.
Preparation Affinity purification
Recommended Dilution ELISA
Storage Store the lyophilized protein at -20°C.
After reconstitution, store the protein at -80°C for 12 months.
Avoid repeated freezing and thawing.
Stability 12 months from date of despatch
Shipping Ambient
Reference Data
Locus ID 952
UniProt ID P28907
Synonyms CD38;T10;cADPr hydrolase 1
Summary CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
Protein Categories ADC Targets, CD Markers, Cytokines, Intracellular Proteins
Protein Families ELISA
Protein Pathways Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism
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Other "CD38" proteins (6)
SKU Description Size Price
LC419752 Lyophilized CD38 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419752 Transient overexpression lysate of CD38 molecule (CD38) (as WB positive control) 100 ug
$436.00
TP721242 Human CD38 Protein (C-His-Avi) 25 ug
$300.00
TP721243 Biotinylated Human CD38 Protein (C-His-Avi) 25 ug
$430.00
TP721244 PE Conjugated Human CD38 Protein (C-His) 25 ug
$430.00
TP721245 APC Conjugated Human CD38 Protein (C-His) 25 ug
$430.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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