CD38 Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-His |
| Predicted MW | The protein has a predicted molecular weight of 31.5kDa and migrates at approximately 35-45kDa on SDS-PAGE with DTT-reduced condition before PE conjugation. |
| Concentration | 25µg size is bottled at 0.1mg/mL concentration. 100 µg size is bottled at lot specific concentration. |
| Purity | >90% |
| Conjugation | PE |
| Presentation State | Purified |
| Buffer | 1xPBS buffer, pH7.4, 0.09% NaN3 with a carrier protein |
| Bioactivity | PositiveThe definition of the active protein (purified and biotinylated) is defined as the protein that can bind to its biological receptor/ligand. For conjugated protein, it is defined with its function to bind to the ScFv of the active CAR-transfected cells in flow cytometry test. |
| Preparation | Affinity Ni-NTA |
| Recommended Dilution | FACS |
| Storage | An unopened vial can be stored at 4°C for 2 weeks or at -20°C and below for six months. This stock solution should be aliquoted and stored at ≤ -70°C to minimize the freeze/thaw cycles. |
| Stability | 6 Months |
| Shipping | Blue Ice |
| Reference Data | |
| RefSeq | NP_001766.2 |
| Locus ID | 952 |
| UniProt ID | P28907 |
| Summary | Cluster of differentiation 38 (CD38) is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed in many immune cells including B cells, T lymphocytes, and NK cells. CD38 is expressed at high levels in some organs like pancreas, liver, kidney, brain, testis, ovary. CD38 can function as either a cell surface receptor or as an enzyme. As the receptor, CD38 can activate T cells and promote cytokine production. As the multifunctional enzyme, CD38 can regulating calcium mediated signal transduction through the production of cyclic ADP-ribose (cADPR) in many types of cells. Clinically, elevated CD38 expression is prognostic marker in chronic lymphocytic leukemia. |
| Protein Families | FACS |
| Protein Pathways | Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CD38" proteins (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| LC419752 | Lyophilized CD38 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY419752 | Transient overexpression lysate of CD38 molecule (CD38) (as WB positive control) | 100 ug |
$436.00
|
|
| TP721242 | Human CD38 Protein (C-His-Avi) | 25 ug |
$300.00
|
|
| TP721243 | Biotinylated Human CD38 Protein (C-His-Avi) | 25 ug |
$430.00
|
|
| TP721245 | APC Conjugated Human CD38 Protein (C-His) | 25 ug |
$430.00
|
|
| TP723927 | Recombinant human CD38 protein with C-terminal human Fc and 6×His tag | 100 ug |
$770.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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