PAK2 (NM_002577) Human Recombinant Protein

CAT#: TP723904

Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2), 100 µg

Product Images

Specifications

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  GPHMTDEEIM EKLRTIVSIG DPKKKYTRYE KIGQGASGTV FTATDVALGQ EVAIKQINLQ KQPKKELIIN EILVMKELKN PNIVNFLDSY LVGDELFVVM EYLAGGSLTD VVTETCMDEA QIAAVCRECL QALEFLHANQ VIHRDIKSDN VLLGMEGSVK LTDFGFCAQI TPEQSKRSTM VGTPYWMAPE VVTRKAYGPK VDIWSLGIMA IEMVEGEPPY LNENPLRALY LIATNGTPEL QNPEKLSPIF RDFLNRCLEM DVEKRGSAKE LLQHPFLKLA KPLSSLTPLI MAAKEAMKSN R
• Tag: Tag Free
• Predicted MW: 33.5 kDa
• Concentration: lot specific
• Purity: >90% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: 25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10% glycerol, 5 mM DTT.
• Bioactivity: Specific activity was determined as 85,806 pmoles/min/µg, according to the Zlyte assay protocol
• Endotoxin: < 0.1 ng/µg of protein (< 1EU/µg)
• Storage: Store at -80°C.
• Stability: Stable at -80°C for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -80°C.

Reference Data

• RefSeq: NP_002568
• Locus ID: 5062
• UniProt ID: Q13177, A8K5M4
• Cytogenetics: 3q29
• Refseq Size: 6139
• Refseq ORF: 1572
• Synonyms: PAK65; PAKgamma
• Summary: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Axon guidance, ErbB signaling pathway, Focal adhesion, MAPK signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway