Ccl5 (NM_013653) Mouse Recombinant Protein

SKU TP723891

Purified recombinant protein of Mouse chemokine (C-C motif) ligand 5 (Ccl5 / RANTES)

Product Data

• Species: Mouse
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Mouse CCL5, the region of Ser24 - Ala91, from gene Accession# NM_013653
• Tag: Tag Free
• Predicted MW: 7.8 kDa
• Concentration: lot specific
• Purity: >90%, as determined by Coomassie stained SDS-PAGE.
• Buffer: 0.1 M Glycine, 0.15 M NaCl buffer, pH 3.0
• Bioactivity: Bioactivity was measured by its ability to chemoattract Baf3-hCCR5 cells in a dose dependent manner.
• Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method
• Storage: Store at -80°C.
• Stability: Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_038681
• Locus ID: 20304
• UniProt ID: P30882
• Cytogenetics: 11 50.66 cM
• RefSeq Size: 579
• RefSeq ORF: 273
• Synonyms: MuRantes; RANTES; Scya5; SISd; TCP228
• Summary: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.[UniProtKB/Swiss-Prot Function]