PGK1 (NM_000291) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-His |
| Predicted MW | 45.5 kDa |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0. |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000282 |
| Locus ID | 5230 |
| UniProt ID | P00558 |
| Cytogenetics | Xq21.1 |
| RefSeq Size | 2439 |
| RefSeq ORF | 1251 |
| Synonyms | HEL-S-68p; MIG10; PGKA |
| Summary | The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. provided by RefSeq, Jan 2014 |
| Protein Categories | Cardiovascular diseases, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycolysis / Gluconeogenesis, Metabolic pathways |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PGK1" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH311172 | PGK1 MS Standard C13 and N15-labeled recombinant protein (NP_000282) | 10 ug |
$3,360.00
|
|
| LC400114 | Lyophilized PGK1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400114 | Transient overexpression lysate of phosphoglycerate kinase 1 (PGK1) (as WB positive control) | 100 ug |
$436.00
|
|
| TP311172 | Recombinant protein of human phosphoglycerate kinase 1 (PGK1), 20 µg | 20 ug |
$737.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.