PDGF AA (PDGFA) (NM_033023) Human Recombinant Protein

CAT#: TP721210

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Purified recombinant protein of Human platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 2


 Product Datasheet for 'TP721210'

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USD 299.00


Availability*
2 Weeks

Size
    • 10 ug


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Specifications

Product Data
Description Purified recombinant protein of Human platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 2
Species Human
Expression Host E. coli
Tag Tag Free
Predicted MW 14.1 kDa
Concentration Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of PBS,pH7.4
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq NP_148983
Locus ID 5154
Refseq Size 2749
Cytogenetics 7p22.3
Refseq ORF 588
Synonyms PDGF-A; PDGF1
Summary This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Protein Families Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton

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