PDGF AA (PDGFA) (NM_033023) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 20.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_148983 |
| Locus ID | 5154 |
| UniProt ID | P04085 |
| Cytogenetics | 7p22.3 |
| RefSeq Size | 2749 |
| RefSeq ORF | 588 |
| Synonyms | PDGF-A; PDGF1 |
| Summary | This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2015 |
| Protein Categories | Cancer: Brain and CNS, Cancer: Lung, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PDGF AA" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH314164 | PDGFA MS Standard C13 and N15-labeled recombinant protein (NP_148983) | 10 ug |
$3,360.00
|
|
| LC409784 | Lyophilized PDGFA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC419225 | Lyophilized PDGFA HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY409784 | Transient overexpression lysate of platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY419225 | Transient overexpression lysate of platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| TP721178 | Purified recombinant protein of Human platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 2 | 10 ug |
$340.00
|
|
| TP721210 | Purified recombinant protein of Human platelet-derived growth factor alpha polypeptide (PDGFA), transcript variant 2 | 10 ug |
$340.00
|
|
Citations
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