TPP1 (NM_000391) Human Recombinant Protein

CAT#: TP721045

Purified recombinant protein of Human tripeptidyl peptidase I (TPP1)

 Product Datasheet for 'TP721045'

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USD 299.00

2 Weeks

    • 10 ug

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Product Data
Description Purified recombinant protein of Human tripeptidyl peptidase I (TPP1)
Species Human
Expression Host HEK293
Tag C-His
Predicted MW 23.94 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 µM filtered solution of 20mM TrisHCl,150mM NaCl,1mM GaCl2,10%Glycerol,pH7.5
Endotoxin Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
Reference Data
RefSeq NP_000382
Locus ID 1200
Refseq Size 3540
Cytogenetics 11p15.4
Refseq ORF 1692
Synonyms CLN2; GIG1; LPIC; SCAR7; TPP-1
Summary This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
Protein Families Protease
Protein Pathways Lysosome


Other Versions

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Rabbit polyclonal antibody to CLN2 (tripeptidyl peptidase I)
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