ERp19 (TXNDC12) (NM_015913) Human Recombinant Protein

CAT#: TP720708

Purified recombinant protein of Human thioredoxin domain containing 12 (endoplasmic reticulum) (TXNDC12)

Specifications

Product Data

• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  His27-Leu168
• Tag: C-His
• Predicted MW: 16.98 kDa
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
• Storage: Store at -80°C.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.

Reference Data

• RefSeq: NP_056997
• Locus ID: 51060
• UniProt ID: O95881
• Cytogenetics: 1p32.3
• Refseq Size: 2412
• Refseq ORF: 516
• Synonyms: AG1; AGR1; ERP16; ERP18; ERP19; hAG-1; hTLP19; PDIA16; TLP19
• Summary: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Glutathione metabolism