GRB2 (NM_002086) Human Recombinant Protein

CAT#: TP720535

Recombinant protein of human growth factor receptor-bound protein 2 (GRB2), transcript variant 1

Request Larger Size Package


 Product Datasheet for 'TP720535'

USD 299.00


Availability*
5 Days

Size
    • 10 ug

Product images

Specifications

Product Data
Description Recombinant protein of human growth factor receptor-bound protein 2 (GRB2), transcript variant 1
Species Human
Expression Host E.Coli
Expression cDNA Clone or AA Sequence A DNA sequence from TrueORF clone, RC200469, encoding the full length polypeptide (Met1-Val217) of human GRB2
Tag C-HIS
Predicted MW 26.3 kDa
Concentration Resuspend the protein to the desired concentration in proper buffer.
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 µM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_002077
Locus ID 2885
Refseq Size 3317
Cytogenetics 17q25.1
Refseq ORF 651
Synonyms ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Summary Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. [UniProtKB/Swiss-Prot Function]
Protein Families
Protein Pathways
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents