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WIBG (PYM1) (NM_001143853) Human Recombinant Protein

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SKU
TP720529
Recombinant protein of human within bgcn homolog (Drosophila) (WIBG), transcript variant 2
Size:
10 ug 500 ug 50 ug 1 mg
  $340.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Met1-Leu204
Tag C-His
Predicted MW 23.7 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 100mM NaCl, 10% Glycerol, pH 8.0.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_001137325
Locus ID 84305
UniProt ID Q9BRP8
Cytogenetics 12q13.2
Synonyms PYM; WIBG
Summary Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "WIBG" proteins (8)
SKU Description Size Price
PH302988 WIBG MS Standard C13 and N15-labeled recombinant protein (NP_115721) 10 ug
$3,360.00
PH327106 WIBG MS Standard C13 and N15-labeled recombinant protein (NP_001137325) 10 ug
$3,360.00
LC410182 Lyophilized WIBG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC428389 Lyophilized WIBG HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY410182 Transient overexpression lysate of within bgcn homolog (Drosophila) (WIBG), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY428389 Transient overexpression lysate of within bgcn homolog (Drosophila) (WIBG), transcript variant 2 (as WB positive control) 100 ug
$436.00
TP302988 Recombinant protein of human within bgcn homolog (Drosophila) (WIBG), transcript variant 1, 20 µg 20 ug
$737.00
TP327106 Recombinant protein of human within bgcn homolog (Drosophila) (WIBG), transcript variant 2, 20 µg 20 ug
$737.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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