Alkaline Phosphatase (ALPL) (NM_000478) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-His |
| Predicted MW | 54.5 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of 20mM HEPES, 150mM NaCl, 2mM MgSO4, 0.1mM ZnCl2, pH 7.5. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000469 |
| Locus ID | 249 |
| UniProt ID | P05186 |
| Cytogenetics | 1p36.12 |
| Synonyms | AP-TNAP; APTNAP; HOPS; HPPA; HPPC; HPPI; HPPO; TNALP; TNAP; TNSALP |
| Summary | This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. provided by RefSeq, Oct 2015 |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Folate biosynthesis, Metabolic pathways |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "Alkaline Phosphatase" proteins (9)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH305692 | ALPL MS Standard C13 and N15-labeled recombinant protein (NP_000469) | 10 ug |
$3,360.00
|
|
| LC400165 | Lyophilized ALPL HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC426804 | Lyophilized ALPL HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC433101 | Lyophilized ALPL HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY400165 | Transient overexpression lysate of alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY426804 | Transient overexpression lysate of alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY433101 | Transient overexpression lysate of alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP305692 | Recombinant protein of human alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
| TP760508 | Purified recombinant protein of Human alkaline phosphatase, liver/bone/kidney (ALPL), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug | 50 ug |
$270.00
|
|
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