LDHA (NM_001135239) Human Recombinant Protein

SKU TP720209M

Recombinant protein of human lactate dehydrogenase A (LDHA), transcript variant 2

Product Data

• Species: Human
• Expression Host: E. coli
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  Met1-Phe332
• Tag: N-His
• Predicted MW: 38.8 kDa
• Concentration: lot specific
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 100mM NaCl, 50% Glycerol, pH 8.0.
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
• Stability: Stable for at least 3 months from date of receipt under proper storage and handling conditions.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_001128711
• Locus ID: 3939
• UniProt ID: P00338
• Cytogenetics: 11p15.1
• Synonyms: GSD11; HEL-S-133P; LDHM; PIG19
• Summary: The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism