LDHA Mouse Monoclonal Antibody [Clone ID: OTI2D11]
$447.00
In Stock*
Specifications
| Product Data | |
| Clone Name | OTI2D11 |
|---|---|
| Application | ELISA (indirect), IHC, IP, WB |
| Recommended Dilution | WB 1:1000, IHC 1:50, IP 2ug/500ul |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human LDHA (NP_005557) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 36.5 kDa |
| Gene Name | lactate dehydrogenase A |
| Database Link | |
| Background | The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. provided by RefSeq |
| Synonyms | GSD11; HEL-S-133P; LDHM; PIG19 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2D11" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| CF500568 | Carrier-free (BSA/glycerol-free) LDHA mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) | 100 ug |
$620.00
|
|
| TA500568AM | LDHA mouse monoclonal antibody, clone OTI2D11 (formerly 2D11), Biotinylated | 100 ul |
$509.00
|
|
| TA500568BM | LDHA mouse monoclonal antibody, clone OTI2D11 (formerly 2D11), HRP conjugated | 100 ul |
$509.00
|
|
| TA500568S | LDHA mouse monoclonal antibody, clone OTI2D11 (formerly 2D11) | 30 ul |
$200.00
|
|
Citations
β-Catenin-Facilitated Glycolytic Reprogramming Fuels TNBC Progression: Therapeutic Blockade with XAV939
Umar, Kahol, Mathur et al
Technol Cancer Res Treat (2026) 25, 15330338261425407 DOI: 10.1177/15330338261425407
Umar, Kahol, Mathur et al
Technol Cancer Res Treat (2026) 25, 15330338261425407 DOI: 10.1177/15330338261425407
Cited by 1
AI Summary: OriGene’s LDHA monoclonal antibody (OTI2D11, mAb# TA500568) was used for immunohistochemical analysis to assess LDHA expression in TNBC patient samples, contributing to the study’s evaluation of glycolytic protein involvement in cancer progression.
Snippet: itle>Respective monoclonal antibodies were procured for β-catenin (β-catenin-1, mAb#M3539;Agilent (CA, USA);PFKP (mAb# 12746;Cell Signaling Technology (MA, USA);LDHA (OTI2D11, mAb# TA500568;Origene (MD, USA);and MCT1 (H-1, mAb#sc-365501;Santa Cruz Biotech Inc (TX, USA). As outlined, immunohistochemical analysis for all glycolytic proteins was conducted on paraffin-embedded breast carci
Showing 1-1 of 1 papers.
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