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CA8 (NM_004056) Human Recombinant Protein

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SKU
TP720093
Purified recombinant protein of Homo sapiens carbonic anhydrase VIII (CA8)
Size:
10 ug 500 ug 50 ug 1 mg
  $205.00
7 Weeks*
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Specifications
Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
Ala2-Gln290
Tag C-His
Predicted MW 34 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 500mM NaCl, 1mM DTT, pH 8.5 .
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_004047
Locus ID 767
UniProt ID P35219
Cytogenetics 8q12.1
Synonyms CA-RP; CA-VIII; CALS; CAMRQ3; CARP
Summary The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. provided by RefSeq, Mar 2016
Protein Categories Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Nitrogen metabolism
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Other "CA8" proteins (4)
SKU Description Size Price
PH310228 CA8 MS Standard C13 and N15-labeled recombinant protein (NP_004047) 10 ug
$3,360.00
LC418248 Lyophilized CA8 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY418248 Transient overexpression lysate of carbonic anhydrase VIII (CA8) (as WB positive control) 100 ug
$436.00
TP310228 Recombinant protein of human carbonic anhydrase VIII (CA8), 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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