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TTI1 (NM_014657) Human Recombinant Protein

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SKU
TP710266
Purified recombinant protein of Human Tel2 interacting protein 1 homolog (S. pombe) (TTI1), full length, with C-terminal DDK tag, expressed in sf9, 20ug
Size:
20 ug
  $540.00
In Stock*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC201622, encoding human full-length TTI1
Tag C-DDK
Predicted MW 121.9 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_055472
Locus ID 9675
UniProt ID O43156
Cytogenetics 20q11.23
RefSeq Size 3931
RefSeq ORF 3267
Synonyms KIAA0406; smg-10
Summary Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
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Other "TTI1" proteins (2)
SKU Description Size Price
LC402361 Lyophilized TTI1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY402361 Transient overexpression lysate of KIAA0406 (KIAA0406) (as WB positive control) 100 ug
$436.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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