beta Catenin (CTNNB1) (NM_001904) Human Recombinant Protein

SKU
TP710027
Recombinant protein of human human catenin (cadherin-associated protein), beta 1(CTNNB1), full length, with C-terminal DDK tag, expressed in sf9 cells
  $540.00
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Specifications
Specifications
Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC208947, encoding human full-length CTNNB1
Tag C-DDK
Predicted MW 85 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_001895
Locus ID 1499
UniProt ID P35222
Cytogenetics 3p22.1
RefSeq Size 3697
RefSeq ORF 2343
Synonyms armadillo; CTNNB; EVR7; MRD19; NEDSDV
Summary The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. provided by RefSeq, Aug 2016
Protein Categories Cancer: Bladder, Cancer: Brain and CNS, Cancer: Endocrine, Cancer: Gastrointestinal, Cancer: Gynecologic, Growth Factors, Intracellular Proteins, Nervous system Diseases
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
Protein Pathways Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Focal adhesion, Leukocyte transendothelial migration, Melanogenesis, Pathogenic Escherichia coli infection, Pathways in cancer, Prostate cancer, Thyroid cancer, Tight junction, Wnt signaling pathway
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Other "beta Catenin" proteins (15)
SKU Description Size Price
PH308947 CTNNB1 MS Standard C13 and N15-labeled recombinant protein (NP_001895) 10 ug
$3,360.00
PH312056 CTNNB1 MS Standard C13 and N15-labeled recombinant protein (NP_001091679) 10 ug
$3,360.00
PH314557 CTNNB1 MS Standard C13 and N15-labeled recombinant protein (NP_001091680) 10 ug
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LC419662 Lyophilized CTNNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420557 Lyophilized CTNNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC420558 Lyophilized CTNNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC426005 Lyophilized CTNNB1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY419662 Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY420557 Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY420558 Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY426005 Transient overexpression lysate of catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 2 (as WB positive control) 100 ug
$665.00
TP308947 Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), 20 µg 20 ug
$867.00
TP312056 Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), 20 µg 20 ug
$867.00
TP314557 Recombinant protein of human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), 20 µg 20 ug
$867.00
TP710124 Recombinant protein of human human catenin (cadherin-associated protein), beta 1(CTNNB1), full length, with N-terminal His tag, expressed in sf9 cells 20 ug
$540.00

file-alt Citations

A Novel Anti-Cancer Agent, 1-(3, 5-Dimethoxyphenyl)-4-[(6-fluoro-2-methoxyquinoxalin-3-yl)aminocarbonyl] piperazine (RX-5902),Interferes with β-Catenin Function through Y593 phospho-p68RNA Helicase
Kost, Yang, Li et al
J. Cell. Biochem. (2015)
Cited by 41
AI Summary: In this study, recombinant p68 protein from OriGene was used to investigate the molecular mechanism by which the anti-cancer agent RX-5902 interferes with β-catenin function via Y593 phospho-p68 RNA helicase.
Snippet: antibody were obtained from Cell Signaling (Danvers, MA). Recombinant Proteins Recombinant β-catenin and p68 protein were purchased from Creative Biomart (Shirley, NY) and Origene (Rockville, MD), respectively.Recombinant β-catenin was used without further ... Cite SaveSaving
Showing 1-1 of 1 papers.
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