ICOS (NM_012092) Human Recombinant Protein

SKU TP700238

Purified recombinant protein of human inducible T-cell co-stimulator (ICOS), with C-terminal Fc/His tag, expressed in human cells, 20 µg

Product Data

• Species: Human
• Expression Host: HEK293T
• Expression cDNA Clone or AA Sequence:
  Protein Sequence

  A DNA sequence from TrueORF clone, [RC207031], encoding the region (Glu21 – Lys140) of human ICOS
• Tag: C-Fc/His
• Predicted MW: 39 kDa
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Buffer: PBS, pH 7.4, 10% glycerol
• Note: For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
• Storage: Store at -80°C.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Shipping: Dry Ice

Reference Data

• RefSeq: NP_036224
• Locus ID: 29851
• UniProt ID: Q9Y6W8
• Cytogenetics: 2q33.2
• RefSeq Size: 2652
• RefSeq ORF: 597
• Synonyms: AILIM; CD278; CVID1
• Summary: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq, Jul 2008]
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway