ICOS Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Mouse Fc and 6×His Tag |
| Predicted MW | The protein has a predicted molecular mass of 41.1 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
| Reconstitution Method | 1. Before opening the tube cap, centrifuge the sample tube at 5000g for 3-5min at room temperature to ensure the lyophilized sample settles down at the bottom of the tube. 2. Calculate the volume for reconstitution (in µL) using the formula: Quantity (mg)/Concentration (mg/mL)x1000 3. Dissolve the lyophilized protein sample in sterile water based on the calculated volume (µL) 4. After adding sterile water, cover the lid and mix by gently tapping the tube 5-10 times. Note: Do not vortex or vigorously pipette the sample. |
| Preparation | Affinity purification |
| Recommended Dilution | ELISA |
| Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
| Stability | 12 months from date of despatch |
| Shipping | Ambient |
| Reference Data | |
| Locus ID | 29851 |
| UniProt ID | Q9Y6W8 |
| Synonyms | ICOS;CD278;AILIM;Inducible T-cell costimulator |
| Summary | The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. |
| Protein Categories | CD Markers, Immune system diseases, Membrane Proteins |
| Protein Families | ELISA |
| Protein Pathways | Cell adhesion molecules (CAMs), Primary immunodeficiency, T cell receptor signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "ICOS" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TP700238 | Purified recombinant protein of human inducible T-cell co-stimulator (ICOS), with C-terminal Fc/His tag, expressed in human cells, 20 µg | 20 ug |
$900.00
|
|
| TP721079 | Purified recombinant protein of Human inducible T-cell co-stimulator (ICOS) | 10 ug |
$260.00
|
|
| TP724017 | Recombinant human ICOS protein with C-terminal human Fc tag | 100 ug |
$855.00
|
|
Citations
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