TIE2 (TEK) (NM_000459) Human Recombinant Protein

SKU
TP700157
Purified recombinant protein of human TEK tyrosine kinase (TEK), endothelial, with C-terminal DDK/His tag, expressed in human cells, 20 µg
  $900.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC600057, encoding the region (Ala23– Leu748) of human TEK
Tag C-DDK/His
Predicted MW 84 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_000450
Locus ID 7010
UniProt ID Q02763
Cytogenetics 9p21.2
RefSeq Size 4787
RefSeq ORF 2244
Synonyms CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1
Summary This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. provided by RefSeq, Feb 2014
Protein Categories CD Markers, Enzyme: Kinases, Growth Factors, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane
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Other "TIE2" proteins (3)
SKU Description Size Price
LC424703 Lyophilized TEK HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY424703 Transient overexpression lysate of TEK tyrosine kinase, endothelial (TEK) (as WB positive control) 100 ug
$436.00
TP762152 Purified recombinant protein of Human TEK tyrosine kinase, endothelial (TEK),Glu53-Leu174, with N-terminal His-ABP tag, expressed in E. coli, 50ug 50 ug
$270.00

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