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TrkA (NTRK1) (NM_002529) Human Recombinant Protein

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SKU
TP700133
Purified recombinant protein of Human neurotrophic tyrosine kinase receptor, type 1, transcript variant 2, with C-terminal DDK/His tag, expressed in human cells
Size:
20 ug
  $900.00
In Stock*
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Frequently Bought Together (1)

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from TrueORF clone, RC600033, encoding the extracellular domain (Ala33-Gly423) of human NTRK1 v2
Tag C-DDK/His
Predicted MW 46 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer PBS, pH 7.4, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_002520
Locus ID 4914
UniProt ID P04629
Cytogenetics 1q23.1
RefSeq Size 2663
RefSeq ORF 1269
Synonyms MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Summary This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. provided by RefSeq, Jul 2008
Protein Categories Cancer: Brain and CNS, Cancer: Endocrine, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Apoptosis, Endocytosis, MAPK signaling pathway, Neurotrophin signaling pathway, Pathways in cancer, Thyroid cancer
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Other "TrkA" proteins (10)
SKU Description Size Price
PH313091 NTRK1 MS Standard C13 and N15-labeled recombinant protein (NP_001012331) 10 ug
$3,360.00
LC400383 Lyophilized NTRK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC419273 Lyophilized NTRK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC423326 Lyophilized NTRK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400383 Transient overexpression lysate of neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 3 (as WB positive control) 100 ug
$665.00
LY419273 Transient overexpression lysate of neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY423326 Transient overexpression lysate of neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 1 (as WB positive control) 100 ug
$665.00
TP313091 Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 1, 20 µg 20 ug
$867.00
TP700134 Purified recombinant protein of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells 20 ug
$900.00
TP762465 Purified recombinant protein of Human neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, Asn440-End, with N-terminal His tag, expressed in E.coli, 50ug 50 ug
$240.00

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