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Pdx1 (NM_008814) Mouse Recombinant Protein

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SKU
TP527421
Purified recombinant protein of Mouse pancreatic and duodenal homeobox 1 (Pdx1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA355501 Pdx1 Antibody - N-terminal region
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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from Mouse cDNA ORF Clone, MR227421, encoding Mouse full-length Pdx1.
Tag C-MYC/DDK
Predicted MW 31.4 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_032840
Locus ID 18609
UniProt ID P52946
Cytogenetics 5 86.84 cM
RefSeq Size 1287
RefSeq ORF 852
Synonyms IDX-1; IPF-1; Ipf1; Mody4; pdx-1; STF-1
Summary Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CCCTTAATGGG-3'.UniProtKB/Swiss-Prot Function
Protein Categories Cytokines, Endocrine and metabolic diseases, Intracellular Proteins, Transciption Factors
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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