OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Usp24 (NM_183225) Mouse Recombinant Protein

Be the first to review this product
SKU
TP526420
Purified recombinant protein of Mouse ubiquitin specific peptidase 24 (Usp24), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA592569 DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
100 ul
$519.00

Other products for "Usp24 or NM_183225"

Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
A DNA sequence from Mouse cDNA ORF Clone, MR226420, encoding Mouse full-length Usp24.
Tag C-MYC/DDK
Predicted MW 294 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_899048
Locus ID 329908
UniProt ID B1AY13
Cytogenetics 4 C7
RefSeq Size 10601
RefSeq ORF 7851
Synonyms 2700066K03Rik; 2810030C21Rik; AI414051; B130021E18; C79851
Summary Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Deubiquitinates DDB2, preventing its proteasomal degradation (By similarity).UniProtKB/Swiss-Prot Function
Protein Categories Enzyme: Peptidases, Intracellular Proteins
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice
Li, Zhang, Wang et al
Biol Direct (2023) 18 (1), 37 DOI: 10.1186/s13062-023-00395-5
Cited by 26
AI Summary: OriGene’s recombinant USP24 protein (#TP526420) was used in deubiquitination assays to demonstrate USP24’s role in stabilizing phosphorylated Runx2, thereby elucidating its contribution to intervertebral disc degeneration under chronic inflammation.
Snippet: assay, the immunoprecipitated Runx2Ser28 from LPS-treated NP-1 cells expressing shUSP24 + HA-Ubiquitin were incubated with various amounts (0, 0.01, 0.02, 0.04, and 0.08 nM) of recombinant USP24 (OriGene;Wxi, Jiangsu, China;#TP526420) in a deubiquitination buffer composed of 50 mM Tris-HCl (pH 7.5) and 10 mM DTT at 37 °C for 1 h. The reaction was halted and resolved using SDS-PAGE loading
FigureFigureFigure
The deubiquitinating enzyme USP24 is a regulator of the UV damage response
Zhang, Nemzow, Chen et al
Cell Rep (2015) 10 (2), 140-7 DOI: 10.1016/j.celrep.2014.12.024
Cited by 55
AI Summary: In this study, OriGene’s USP24 shRNA (OriGene, sc-92358-V) and USP24 expression plasmid (OriGene, RC217247) were used to manipulate USP24 levels in human cells, enabling the authors to demonstrate USP24’s role in regulating p53 stability and the cellular response to UV-induced DNA damage.
FigureFigure
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products