C3 (NM_009778) Mouse Recombinant Protein
SKU
TP526388
Purified recombinant protein of Mouse complement component 3 (C3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
$1,020.00
In Stock*
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-MYC/DDK |
| Predicted MW | 186.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_033908 |
| Locus ID | 12266 |
| UniProt ID | P01027 |
| Cytogenetics | 17 29.72 cM |
| RefSeq Size | 5147 |
| RefSeq ORF | 4989 |
| Synonyms | AI255234; ASP; HSE-MSF; Plp |
| Summary | This gene encodes complement protein C3 which plays a central role in the classical, alternative and lectin activation pathways of the complement system. The encoded preproprotein undergoes a multi-step processing to generate various functional peptides. Mice deficient in the encoded protein fail to clear bacteria from the blood stream upon infection, display diminished airway hyperresponsiveness and lung eosinophilia upon allergen-induced pulmonary allergy, and develop severe lung injury after deposition of IgG immune complexes. Deficiency of the homolog of the encoded protein in humans was found to be associated with increased susceptibility to infections, age-related macular degeneration, and atypical hemolytic uremic syndrome. provided by RefSeq, Mar 2015 |
| Protein Categories | Cardiovascular diseases, Growth Factors, Immune system diseases, Intracellular Proteins, Nervous system Diseases, Secreated Proteins |
Reviews
Documents
| FAQs |
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Resources
| Recombinant Protein Resources |
Other "C3" proteins (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH315069 | C3 MS Standard C13 and N15-labeled recombinant protein (NP_000055) | 10 ug |
$3,360.00
|
|
| LC424934 | Lyophilized C3 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY424934 | Transient overexpression lysate of complement component 3 (C3) (as WB positive control) | 100 ug |
$665.00
|
|
| TP315069 | Recombinant protein of human complement component 3 (C3), 20 µg | 20 ug |
$737.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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