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Ubash3a (NM_177823) Mouse Recombinant Protein

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SKU
TP522490
Purified recombinant protein of Mouse ubiquitin associated and SH3 domain containing, A (Ubash3a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR222490 representing NM_177823
Red=Cloning site Green=Tags(s)

MAAGETQLYAKVSNKLKGRSTPSLLDPLLAMGFPTHTALKALAATGRKTAEAAADWLHGHCNDPSLDDPI
PQEYALFLCPTGPLLEKLQEFWRESRRQCAKNRAHEVFPHVTLCDFFTCEDQKVECLYEALRRAGDRILG
SFPTLVPLVLHSSISYLGFFINDSPADAIREFAMAFATEAAVLADCTIKPCTKQLHLTLAHKFYPHHQRT
LEQLAKAIQPSHSCQWTAALYSRDMRFVHYQTLKALFQYKPQNADELMLSAGDYIFVDPTQQEEASEGWA
IGISHRTGCRGFLPENYTERANEADTWVKHRTYTFNLAMDLNSRKDFEASCRGNGEPHTPSMSKSVSSIQ
ALQATISRRGILVVRHGERVDQVFGKSWLQQCTTADGKYYRPDLNFPRSLPRRSNGIKDFENDPPLSSCG
IFQARLAGEALLDSGVRVTAVFASPALRCVQTAKHILEELKLEKKLKIRVEPGIFEWMKWEASKATLTFL
TLEELKEANFNVDLDYRPALPRCSLMPAESYDQYVERCAVSMGQIINTCPQDMGITLIVSHSSALDSCTR
PLLGLPPRECGDFAQLVRKIPSLGMCFCEENREDGKWDLVNPPVKTLTHGANSVFNWRNWISSN

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 70.1 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_808491
Locus ID 328795
UniProt ID Q3V3E1
Cytogenetics 17 A3.3- B1
RefSeq Size 2953
RefSeq ORF 1872
Synonyms 5830413C03Rik; C330001M22; Sts-2; TULA; TULA-1
Summary Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain (By similarity). Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation.UniProtKB/Swiss-Prot Function
Protein Categories Cytokines, Growth Factors, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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