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Atp7b (NM_007511) Mouse Recombinant Protein

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SKU
TP518768
Purified recombinant protein of Mouse ATPase, Cu++ transporting, beta polypeptide (Atp7b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Size:
20 ug
  $1,020.00
4 Weeks*
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Specifications
Specifications
Product Data
Species Mouse
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>MR218768 representing NM_007511
Red=Cloning site Green=Tags(s)

MDPRKNLASVGTMPEQERQVTAKEASRKILSKLALPGRPWEQSMKQSFAFDNVGYEGGLDSTSSSPAATD
VVNILGMTCHSCVKSIEDRISSLKGIVNIKVSLEQGSATVRYVPSVMNLQQICLQIEDMGFEASAAEGKA
ASWPSRSSPAQEAVVKLRVEGMTCQSCVSSIEGKIRKLQGVVRIKVSLSNQEAVITYQPYLIQPEDLRDH
ICDMGFEAAIKNRTAPLRLGPIDVNKLESTNLKKETVSPVQISNHFETLGHQGSYLATLPLRIDGMHCKS
CVLNIEGNIGQLPGVQNIHVSLENKTAQIQYDPSCVTPMFLQTAIEALPPGHFKVSLPDGVEENEPQSGS
SQRHQEQGPGRTAVLTISGITCASSVQPIEDMLSQRKGVQQTSISLAEGTGAVLYDPSIVSLDELRTAVE
DMGFEVSVNSETFTINPVRNFKSGNSVPQTMGDIAGSVQKMAPDTRGLPTHQGPGHSSETPSSPGATASQ
KCFVQIKGMTCASCVSNIERSLQRHAGILSVLVALMSGKAEVKYDPEIIQSPRIAQLIQDLGFEASVMED
NTVSEGDIELIITGMTCASCVHNIESKLTRTNGITYASVALATSKAHVKFDPEIVGPRDIIKIIEEIGFH
ASLAQRNPNAHHLDHKTEIKQWKKSFLCSLVFGIPVMGLMVYMLIPSSTPQETMVLDHNIIPGLSVLNLI
FFILCTFVQFLGGWYFYVQAYKSLRHRSANMDVLIVLATTIAYAYSLVILVVAVAEKAEKSPVTFFDTPP
MLFVFIALGRWLEHVAKSKTSEALAKLMSLQATEATVVTLGEDNLILREEQVPMELVQRGDVIKVVPGGK
FPVDGKVLEGNTMADESLITGEAMPVTKKPGSIVIAGSINAHGSVLLKATHVGNDTTLAQIVKLVEEAQM
SKAPIQQLADRFSGYFVPFIIIISTLTLVVWIVIGFVDFGVVQKYFPSPSKHISQTEVIIRFAFQTSITV
LCIACPCSLGLATPTAVMVGTGVAAQNGVLIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRFLLLADV
ATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYSTDFQAVPGCGISCKVSNVEGILARSDL
TAHPVGVGNPPTGEGAGPQTFSVLIGNREWMRRNGLTISSDISDAMTDHEMKGQTAILVAIDGVLCGMIA
IADAVKPEAALAIYTLKSMGVDVALITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNEGKKVA
MVGDGVNDSPALAQADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRVNLVLALIYNM
VGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYRKPDLERYEAQAHGRMKPLSASQVSVH
IGMDDRRRDSPRATAWDQVSYVSQVSLSSLTSDRLSRHGGAAEDGGDKWSLLLSDRDEEQCI

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 157.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_031537
Locus ID 11979
UniProt ID Q64446
Cytogenetics 8 10.78 cM
RefSeq Size 4711
RefSeq ORF 4386
Synonyms Atp7a; tx; WND
Summary Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.UniProtKB/Swiss-Prot Function
Protein Categories Membrane Proteins
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Documents
Resources

file-alt Citations

Neutrophil extracellular traps delivering lactylated S100a9 aggravate neuronal cuproptosis by regulating Ttr/Commd1/Atp7b axis after traumatic brain injury
Xu, Zhang, Liu et al
Redox Biol (2026) 97, 104408 DOI: 10.1016/j.redox.2026.104408
AI Summary: OriGene’s Myc-Atp7b (catalog number TP518768) was used in protein interaction assays to investigate the molecular mechanism by which neuronal Ttr disrupts the Commd1-Atp7b axis, contributing to copper accumulation and neuronal cuproptosis after traumatic brain injury.
Snippet: Different proportions of His-Ttr (CSB-MP025270MO, Cusabio, Wuhan, CHN) and Myc-Atp7b (TP518768, OriGene, Rockville, USA) were incubated with GST-Commd1 or GST together in TBST buffer with 5% glycerol for 2h at 4°C
Showing 1-1 of 1 papers.
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