C4b (NM_009780) Mouse Recombinant Protein
Specifications
| Product Data | |
| Species | Mouse |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | Myc-DDK |
| Predicted MW | 192.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate Bradford method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris.HCl, pH7.3, 100 mM glycine, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C after receiving vials. |
| Stability | Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_033910 |
| Locus ID | 12268 |
| UniProt ID | P01029 Q3TYN1 |
| Cytogenetics | 17 18.29 cM |
| RefSeq Size | 5427 |
| RefSeq ORF | 5214 |
| Synonyms | C4; Ss |
| Summary | Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens (By similarity).UniProtKB/Swiss-Prot Function |
| Protein Categories | Immune system diseases, Intracellular Proteins, Secreated Proteins |
Reviews
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