NCF2 (NM_001127651) Human Recombinant Protein

CAT#: TP325899

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Recombinant protein of human neutrophil cytosolic factor 2 (NCF2), transcript variant 2


 Product Datasheet for 'TP325899'

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USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human neutrophil cytosolic factor 2 (NCF2), transcript variant 2
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 59.6 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_001121123
Locus ID 4688
Cytogenetics 1q25.3
Refseq ORF 1578
Synonyms NCF-2; NOXA2; P67-PHOX; P67PHOX
Summary This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Protein Families Druggable Genome
Protein Pathways Leukocyte transendothelial migration

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