DUOX1 (NM_175940) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 177.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_787954 |
| Locus ID | 53905 |
| UniProt ID | Q9NRD9 |
| Cytogenetics | 15q21.1 |
| RefSeq Size | 5501 |
| RefSeq ORF | 4653 |
| Synonyms | LNOX1; NOXEF1; THOX1 |
| Summary | The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. provided by RefSeq, Jul 2012 |
| Protein Categories | Cytokines, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "DUOX1" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH323832 | DUOX1 MS Standard C13 and N15-labeled recombinant protein (NP_787954) | 10 ug |
$3,360.00
|
|
| PH323975 | DUOX1 MS Standard C13 and N15-labeled recombinant protein (NP_059130) | 10 ug |
$3,360.00
|
|
| LC413789 | Lyophilized DUOX1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY413789 | Transient overexpression lysate of dual oxidase 1 (DUOX1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| TP323975 | Purified recombinant protein of Homo sapiens dual oxidase 1 (DUOX1), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.