UNC45B (NM_173167) Human Recombinant Protein
SKU
TP323751
Recombinant protein of human unc-45 homolog B (C. elegans) (UNC45B), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 103.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_775259 |
| Locus ID | 146862 |
| UniProt ID | Q8IWX7 |
| Cytogenetics | 17q12 |
| RefSeq Size | 5694 |
| RefSeq ORF | 2793 |
| Synonyms | CMYA4; CTRCT43; MFM11; SMUNC45; UNC-45B; UNC45 |
| Summary | This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. provided by RefSeq, Apr 2015 |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "UNC45B" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH323751 | UNC45B MS Standard C13 and N15-labeled recombinant protein (NP_775259) | 10 ug |
$3,360.00
|
|
| LC403546 | Lyophilized UNC45B HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403546 | Transient overexpression lysate of unc-45 homolog B (C. elegans) (UNC45B), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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