XPF (ERCC4) (NM_005236) Human Recombinant Protein

CAT#: TP323300

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Recombinant protein of human excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4)


 Product Datasheet for 'TP323300'

  View other "ERCC4" proteins (3)

USD 788.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4)
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 104.3 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_005227
Locus ID 2072
Refseq Size 2751
Cytogenetics 16p13.12
Refseq ORF 2748
Synonyms ERCC11; FANCQ; RAD1; XFEPS; XPF
Summary The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome
Protein Pathways Nucleotide excision repair

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