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SP3 (NM_003111) Human Recombinant Protein

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SKU
TP322027
Recombinant protein of human Sp3 transcription factor (SP3), transcript variant 1, 20 µg
Size:
20 ug 1 mg 100 ug
  $867.00
In Stock*
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Frequently Bought Together (2)

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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC222027 protein sequence
Red=Cloning site Green=Tags(s)

MTAPEKPVKQEEMAALDVDSGGGGGGGGGHGEYLQQQQQHGNGAVAAAAAAQDTQPSPLALLAATCSKIG
PPSPGDDEEEAAAAAGAPAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYV
LPLQNLQNQQIFSVAPGSDSSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSDNGGINQESSQIQIIPGS
NQTLLASGTPSANIQNLIPQTGQVQVQGVAIGGSSFPGQTQVVANVPLGLPGNITFVPINSVDLDSLGLS
GSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQLPVTIDSTGILQ
QNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQT
IHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQVTWQTFQVQGVQNLQNLQIQNTAAQQITLT
PVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTVTVNSIDSAGIQLHPGENADSPADIRIKEEEPDPEEW
QLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEGKRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGK
VYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHI
KTHQNKKGIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQ
LVTVSGNETME

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 81.7 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_003102
Locus ID 6670
UniProt ID Q02447
Cytogenetics 2q31.1
RefSeq Size 3920
RefSeq ORF 2343
Synonyms SPR2
Summary This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. provided by RefSeq, Feb 2010
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, Transcription Factors
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Documents
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Other "SP3" proteins (5)
SKU Description Size Price
PH322027 SP3 MS Standard C13 and N15-labeled recombinant protein (NP_003102) 10 ug
$3,360.00
LC400394 Lyophilized SP3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC401084 Lyophilized SP3 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY400394 Transient overexpression lysate of Sp3 transcription factor (SP3), transcript variant 2 (as WB positive control) 100 ug
$665.00
LY401084 Transient overexpression lysate of Sp3 transcription factor (SP3), transcript variant 1 (as WB positive control) 100 ug
$665.00

file-alt Citations

microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway
Riedel, Fischer, Ly et al
Sci Rep (2018) 8 (1), 17779 DOI: 10.1038/s41598-018-36217-2
Cited by 20
AI Summary: In this study, OriGene's human XYLT1 cDNA clone (RC211419) and Sp1 cDNA clone (RC211352) were used to investigate the regulatory effects of microRNA-29b and Sp1 on xylosyltransferase-I expression in human dermal fibroblasts.
FigureFigureFigure
Showing 1-1 of 1 papers.
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