JPT1 (NM_016185) Human Recombinant Protein
SKU
TP321865
Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 15.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_057269 |
| Locus ID | 51155 |
| UniProt ID | Q9UK76 |
| Cytogenetics | 17q25.1 |
| RefSeq Size | 1602 |
| RefSeq ORF | 462 |
| Synonyms | ARM2; HN1; HN1A |
| Summary | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).UniProtKB/Swiss-Prot Function |
| Protein Categories | Cytokines, Intracellular Proteins |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "JPT1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH307344 | HN1 MS Standard C13 and N15-labeled recombinant protein (NP_001002033) | 10 ug |
$3,360.00
|
|
| PH321865 | HN1 MS Standard C13 and N15-labeled recombinant protein (NP_057269) | 10 ug |
$3,360.00
|
|
| LC414136 | Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424172 | Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414136 | Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424172 | Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP307344 | Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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