JPT1 (NM_016185) Human Mass Spec Standard
Specifications
| Product Data | |
| Tag | C-Myc/DDK |
|---|---|
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC221865 |
| Predicted MW | 15.8 kDa |
| Protein Sequence | |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Storage | Store at -80°C. Avoid repeated freeze-thaw cycles. |
| Stability | Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_057269 |
| RefSeq Size | 1602 |
| RefSeq ORF | 462 |
| Synonyms | ARM2; HN1; HN1A |
| Locus ID | 51155 |
| UniProt ID | Q9UK76 |
| Cytogenetics | 17q25.1 |
| Summary | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "JPT1" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH307344 | HN1 MS Standard C13 and N15-labeled recombinant protein (NP_001002033) | 10 ug |
$3,360.00
|
|
| LC414136 | Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC424172 | Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414136 | Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
| LY424172 | Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| TP307344 | Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 3, 20 µg | 20 ug |
$867.00
|
|
| TP321865 | Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 1, 20 µg | 20 ug |
$867.00
|
|
Citations
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.