JPT1 (NM_016185) Human Mass Spec Standard

SKU
PH321865
HN1 MS Standard C13 and N15-labeled recombinant protein (NP_057269)
  $3,360.00
3 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221865
Predicted MW 15.8 kDa
Protein Sequence
Protein Sequence
>RC221865 representing NM_016185
Red=Cloning site Green=Tags(s)

MTTTTTFKGVDPNSRNSSRVLRPPGGGSNFSLGFDEPTEQPVRKNKMASNIFGTPEENQASWAKSAGAKS
SGGREDLESSGLQRRNSSEASSGDFLDLKGEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPS
RRNPPGGKSSLVLG

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with U- 13C6, 15N4-L-Arginine and U- 13C6, 15N2-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Storage Store at -80°C. Avoid repeated freeze-thaw cycles.
Stability Stable for 3 months from receipt of products under proper storage and handling conditions.
Shipping Dry Ice
Reference Data
RefSeq NP_057269
RefSeq Size 1602
RefSeq ORF 462
Synonyms ARM2; HN1; HN1A
Locus ID 51155
UniProt ID Q9UK76
Cytogenetics 17q25.1
Summary Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).UniProtKB/Swiss-Prot Function
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Other "JPT1" proteins (7)
SKU Description Size Price
PH307344 HN1 MS Standard C13 and N15-labeled recombinant protein (NP_001002033) 10 ug
$3,360.00
LC414136 Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC424172 Lyophilized HN1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY414136 Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 1 (as WB positive control) 100 ug
$436.00
LY424172 Transient overexpression lysate of hematological and neurological expressed 1 (HN1), transcript variant 3 (as WB positive control) 100 ug
$436.00
TP307344 Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 3, 20 µg 20 ug
$867.00
TP321865 Recombinant protein of human hematological and neurological expressed 1 (HN1), transcript variant 1, 20 µg 20 ug
$867.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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