CD44 (NM_000610) Human Recombinant Protein
SKU
TP321771L
Recombinant protein of human CD44 molecule (Indian blood group) (CD44), transcript variant 1, 1 mg
$9,200.00
6 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 79.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | ELISA binding assay (PMID: 26140900) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_000601 |
| Locus ID | 960 |
| UniProt ID | P16070 |
| Cytogenetics | 11p13 |
| RefSeq Size | 5748 |
| RefSeq ORF | 2226 |
| Synonyms | CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1 |
| Summary | The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. provided by RefSeq, Jul 2008 |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
| Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Citations
A CD44 specific peptide developed by phage display for targeting gastric cancer
Zhang, Jia, Wang et al
Biotechnol. Lett. (2015)
Zhang, Jia, Wang et al
Biotechnol. Lett. (2015)
Cited by 24
AI Summary: OriGene's recombinant human CD44 protein, produced in HEK 293 cells, was used as the immobilized target for phage display screening to identify a CD44-specific peptide for gastric cancer targeting in this study.
Snippet: Library (New England BioLabs). Briefly, 5 μg CD44 which generated form human HEK 293 cells (OriGene) in 100 μl 0.1 M NaHCO 3 (pH 8.6) was immobilized on an ELISA plate at 4 °C overnight. Approx. 10 11 plaque-forming ... Cite SaveSaving
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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