NCOA7 (NM_181782) Human Recombinant Protein

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SKU
TP321673
Recombinant protein of human nuclear receptor coactivator 7 (NCOA7), transcript variant 1, 20 µg
  $737.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC221673 representing NM_181782
Red=Cloning site Green=Tags(s)

MDTKEEKKERKQSYFARLKKKKQAKQNAETASAVATRTHTGKEDNNTVVLEPDKCNIAVEEEYMTDEKKK
RKSNQLKEIRRTELKRYYSIDDNQNKTHDKKEKKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVE
LNKLFTHTIVPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSST
SEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIAL
YNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGEKIMTSDSRPIVP
LEKSTGHTPTKPSGSSVSEKLKKLDSSRETSHGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLE
ELSSQTGGGMHKKDTLKECLSLDPEERKKAESQINNSAVEMQVQSALAFLGTENDVELKGALDLETCEKQ
DIMPEVDKQSGSPESRVENTLNIHEDLDKVKLIEYYLTKNKEGPQVSENLQKTELSDGKSIEPGGIDITL
SSSLSQAGDPITEGNKEPDKTWVKKGEPLPVKLNSSTEANVIKEALDSSLESTLDNSCQGAQMDNKSEVQ
LWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV
DHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEDEDE
EVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGTSLKTLYRKSASLDSPVLLVIKDMDN
QIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLY
HGRSNSCSTFNNDILSKKEDFIVQDLEVWAFD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 106 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_861447
Locus ID 135112
UniProt ID Q8NI08
Cytogenetics 6q22.31-q22.32
RefSeq Size 5550
RefSeq ORF 2826
Synonyms dJ187J11.3; ERAP140; ESNA1; Nbla00052; Nbla10993; NCOA7-AS; TLDC4
Summary Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.UniProtKB/Swiss-Prot Function
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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Other "NCOA7" proteins (3)
SKU Description Size Price
PH321673 NCOA7 MS Standard C13 and N15-labeled recombinant protein (NP_861447) 10 ug
$3,360.00
LC405613 Lyophilized NCOA7 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY405613 Transient overexpression lysate of nuclear receptor coactivator 7 (NCOA7), transcript variant 1 (as WB positive control) 100 ug
$665.00

file-alt Citations

The Ncoa7 locus regulates V-ATPase formation and function, neurodevelopment and behaviour
Castroflorio, den Hoed, Svistunova et al
Cell Mol Life Sci (2020)
Cited by 55
AI Summary: OriGene’s full-length NCOA7 recombinant protein was used to investigate protein-lipid interactions, helping to elucidate the molecular function of NCOA7 in neuronal V-ATPase assembly and lysosomal regulation in this study.
Snippet: Members of the Tre2/Bub2/Cdc16 (TBC), lysin motif (LysM), domain catalytic (TLDc) protein family are associated with multiple neurodevelopmental disorders,.;Full-length NCOA7 recombinant protein (OriGene) was incubated with PIPs strip Membrane (ThermoFisher) containing 100 pmol of lipid per spot overnight
Showing 1-1 of 1 papers.
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