PANK1 (NM_148977) Human Recombinant Protein

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SKU
TP321538
Recombinant protein of human pantothenate kinase 1 (PANK1), transcript variant alpha, 20 µg
  $867.00
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Specifications
Specifications
Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Protein Sequence
>RC221538 representing NM_148977
Red=Cloning site Green=Tags(s)

MLKLVGGGGGQDWACSVAGTSLGGEEAAFEVARPGDQGKAGGGSPGWGCAGIPDSAPGAGVLQAGAVGPA
RGGQGAEEVGESAGGGEERRVRHPQAPALRLLNRKPQGGSGEIKTPENDLQRGRLSRGPRTAPPAPGMGD
RSGQQERSVPHSPGAPVGTSAAAVNGLLHNGFHPPPVQPPHVCSRGPVGGSDAAPQRLPLLPELQPQPLL
PQHDSPAKKCRLRRRMDSGRKNRPPFPWFGMDIGGTLVKLVYFEPKDITAEEEQEEVENLKSIRKYLTSN
TAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPSCAMHRFIQMGSEKNFSSLHTTLCATGGGAFKFEEDF
RMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPECYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVS
ILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGDYERFGLQG
SAVASSFGNMMSKEKRDSISKEDLARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLA
YAMDFWSKGQLKALFLEHEGYFGAVGALLELFKMTDDK

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-Myc/DDK
Predicted MW 64.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Shipping Dry Ice
Reference Data
RefSeq NP_683878
Locus ID 53354
UniProt ID Q8TE04
Cytogenetics 10q23.31
RefSeq Size 3367
RefSeq ORF 1794
Synonyms PANK
Summary This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). provided by RefSeq, Apr 2011
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pantothenate and CoA biosynthesis
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Other "PANK1" proteins (9)
SKU Description Size Price
PH321519 PANK1 MS Standard C13 and N15-labeled recombinant protein (NP_612189) 10 ug
$3,360.00
PH321538 PANK1 MS Standard C13 and N15-labeled recombinant protein (NP_683878) 10 ug
$3,360.00
LC407715 Lyophilized PANK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC407716 Lyophilized PANK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LC408718 Lyophilized PANK1 HEK293T cell transient overexpression lysate (as WB positive control) 20 ug
$206.00
LY407715 Transient overexpression lysate of pantothenate kinase 1 (PANK1), transcript variant alpha (as WB positive control) 100 ug
$665.00
LY407716 Transient overexpression lysate of pantothenate kinase 1 (PANK1), transcript variant beta (as WB positive control) 100 ug
$436.00
LY408718 Transient overexpression lysate of pantothenate kinase 1 (PANK1), transcript variant gamma (as WB positive control) 100 ug
$436.00
TP321519 Recombinant protein of human pantothenate kinase 1 (PANK1), transcript variant gamma, 20 µg 20 ug
$867.00

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