PANK1 (NM_138316) Human Recombinant Protein

CAT#: TP321519

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Recombinant protein of human pantothenate kinase 1 (PANK1), transcript variant gamma


 Product Datasheet for 'TP321519'

  View other "PANK1" proteins (9)

USD 748.00


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Size
    • 20 ug


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Specifications

Product Data
Description Recombinant protein of human pantothenate kinase 1 (PANK1), transcript variant gamma
Species Human
Expression Host HEK293T
Tag C-Myc/DDK
Predicted MW 35.4 kDa
Concentration >50 ug/mL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Preparation Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Reference Data
RefSeq NP_612189
Locus ID 53354
Refseq Size 2525
Cytogenetics 10q23.31
Refseq ORF 942
Synonyms PANK
Summary This gene encodes a member of the pantothenate kinase family. Pantothenate kinases are key regulatory enzymes in the biosynthesis of coenzyme A (CoA). The encoded protein catalyzes the first and rate-limiting enzymatic reaction in CoA biosynthesis and is regulated by CoA through feedback inhibition. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene and an intronic miRNA on the same strand are co-regulated by the tumor suppressor p53 (see PMID 20833636). [provided by RefSeq, Apr 2011]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Pantothenate and CoA biosynthesis

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Other Versions

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