MYSM1 (NM_001085487) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 94.9 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_001078956 |
| Locus ID | 114803 |
| UniProt ID | Q5VVJ2 |
| Cytogenetics | 1p32.1 |
| RefSeq Size | 2589 |
| RefSeq ORF | 2484 |
| Synonyms | 2A-DUB; 2ADUB; BMFS4 |
| Summary | Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation (PubMed:28115216, PubMed:26220525).UniProtKB/Swiss-Prot Function |
| Protein Categories | Cardiovascular diseases, Enzyme: Peptidases, Intracellular Proteins |
| Protein Families | Protease |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "MYSM1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH320811 | MYSM1 MS Standard C13 and N15-labeled recombinant protein (NP_001078956) | 10 ug |
$3,360.00
|
|
| LC421326 | Lyophilized MYSM1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY421326 | Transient overexpression lysate of Myb-like, SWIRM and MPN domains 1 (MYSM1) (as WB positive control) | 100 ug |
$665.00
|
|
Citations
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