CDCP1 (NM_022842) Human Recombinant Protein
SKU
TP320633
Recombinant protein of human CUB domain containing protein 1 (CDCP1), transcript variant 1, 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 92.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | ELISA assay (PMID: 26227951) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_073753 |
| Locus ID | 64866 |
| UniProt ID | Q9H5V8 |
| Cytogenetics | 3p21.31 |
| RefSeq Size | 6017 |
| RefSeq ORF | 2508 |
| Synonyms | CD318; SIMA135; TRASK |
| Summary | This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. provided by RefSeq, May 2013 |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
| Protein Families | ES Cell Differentiation/IPS, Transmembrane |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CDCP1" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH320633 | CDCP1 MS Standard C13 and N15-labeled recombinant protein (NP_073753) | 10 ug |
$3,360.00
|
|
| LC402953 | Lyophilized CDCP1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406018 | Lyophilized CDCP1 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY402953 | Transient overexpression lysate of CUB domain containing protein 1 (CDCP1), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
| LY406018 | Transient overexpression lysate of CUB domain containing protein 1 (CDCP1), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer
Al-Awadhi, Salvador, Law et al
Mar Drugs (2017) 15 (9) DOI: 10.3390/md15090290
Al-Awadhi, Salvador, Law et al
Mar Drugs (2017) 15 (9) DOI: 10.3390/md15090290
AI Summary: In this study, the recombinant protein of human CUB domain containing protein 1 (CDCP1), transcript variant 1 (OriGene; TP320633), was used as a substrate to evaluate the inhibitory effect of kempopeptin C on protease-mediated cleavage relevant to breast cancer cell invasion.
Snippet: …Cached;Recombinant human matriptase (R&D Systems;3946-SE-010) and recombinant human desmoglein 2 FC Chimera (R&D Systems;947-DM-100) or recombinant protein of human CUB domain containing protein 1 (CDCP1), transcript variant 1 (OriGene;TP320633, Rockville, MD, USA) were incubated in an enzyme to substrate ratio (1:5) for 30 min, 1 h, 2 h or 3 h, pH 9.0, at 37 °C
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling
Sandercock, Rust, Guillard et al
Mol. Cancer (2015) 14, 147 DOI: 10.1186/s12943-015-0415-0
Sandercock, Rust, Guillard et al
Mol. Cancer (2015) 14, 147 DOI: 10.1186/s12943-015-0415-0
Cited by 53
AI Summary: OriGene’s recombinant full-length CDCP1 transcript variant 1 protein (cat# TP320633) was used in direct ELISA assays to assess the binding specificity of anti-CDCP1 antibodies in this study.
Snippet: (A) GeoMean fluorescence signals for anti-CDCP1 antibodies binding to NCI-H358 cells that were untreated, or treated with non-targetting or CDCP1-targetting siRNA. (B) Binding of anti-CDCP1 antibodies to recombinant full-length CDCP1 transcript variant 1 (Origene cat# TP320633) in a direct ELISA. (PPTX 120 kb)
Showing 1-2 of 2 papers.
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