PCSK9 (NM_174936) Human Recombinant Protein
SKU
TP320000
Recombinant protein of human proprotein convertase subtilisin/kexin type 9 (PCSK9), 20 µg
$867.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 71 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_777596 |
| Locus ID | 255738 |
| UniProt ID | Q8NBP7 |
| Cytogenetics | 1p32.3 |
| RefSeq Size | 3636 |
| RefSeq ORF | 2076 |
| Synonyms | FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9 |
| Summary | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2014 |
| Protein Categories | Cardiovascular diseases, Enzyme: Peptidases, Intracellular Proteins, Secreated Proteins |
| Protein Families | Secreted Protein |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PCSK9" proteins (7)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH320000 | PCSK9 MS Standard C13 and N15-labeled recombinant protein (NP_777596) | 10 ug |
$3,360.00
|
|
| LC403563 | Lyophilized PCSK9 HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403563 | Transient overexpression lysate of proprotein convertase subtilisin/kexin type 9 (PCSK9) (as WB positive control) | 100 ug |
$665.00
|
|
| TP700053 | Recombinant protein of secreted form of human proprotein convertase subtilisin/kexin type 9 (PCSK9) | 20 ug |
$900.00
|
|
| TP720768 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9) | 10 ug |
$275.00
|
|
| TP721051 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9), D374Y mutant. | 10 ug |
$275.00
|
|
| TP723879 | Purified recombinant protein of Human proprotein convertase subtilisin/kexin type 9 (PCSK9) | 10 ug |
$465.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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