GCOM1 (POLR2M) (NM_015532) Human Recombinant Protein
SKU
TP319621
Recombinant protein of human glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A), transcript variant 1, 20 µg
$737.00
In Stock*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 41.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Bioactivity | WB positive control (PMID: 26116512) |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_056347 |
| Locus ID | 81488 |
| UniProt ID | Q6EEV4 |
| Cytogenetics | 15q21.3 |
| RefSeq Size | 4139 |
| RefSeq ORF | 1104 |
| Synonyms | GCOM1; Gdown; Gdown1; GRINL1A |
| Summary | This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781. provided by RefSeq, Oct 2013 |
| Protein Families | Druggable Genome, Ion Channels: Other |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "GCOM1" proteins (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH319621 | GRINL1A MS Standard C13 and N15-labeled recombinant protein (NP_056347) | 10 ug |
$3,360.00
|
|
| LC414481 | Lyophilized POLR2M HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY414481 | Transient overexpression lysate of glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A), transcript variant 1 (as WB positive control) | 100 ug |
$436.00
|
|
Citations
Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins
Montesinos-Rongen, Purschke, Brunn et al
J. Immunol. (2015) 195 (3), 1312-9 DOI: 10.4049/jimmunol.1402341
Montesinos-Rongen, Purschke, Brunn et al
J. Immunol. (2015) 195 (3), 1312-9 DOI: 10.4049/jimmunol.1402341
Cited by 42
AI Summary: OriGene’s recombinant GRINL1A protein was used in this study to assess the binding specificity of recombinant antibodies derived from primary CNS lymphoma, helping demonstrate their recognition of CNS-expressed proteins.
Snippet: A total of 0.1 or 0.5 μg recombinant GRINL1A (OriGene Technologies, Rockville, MD) was separated on 4–12% Bis-Tris protein gels and transferred to nitrocellulose membranes, according to the manufacturer's protocol (Life Technologies). ... Cite SaveSaving
Showing 1-1 of 1 papers.
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