PDE5A (NM_033430) Human Recombinant Protein
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 94.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_236914 |
| Locus ID | 8654 |
| UniProt ID | O76074 |
| Cytogenetics | 4q26 |
| RefSeq Size | 6836 |
| RefSeq ORF | 2499 |
| Synonyms | CGB-PDE; CN5A; PDE5 |
| Summary | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. provided by RefSeq, Jul 2008 |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Progesterone-mediated oocyte maturation, Purine metabolism |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "PDE5A" proteins (5)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH318974 | PDE5A MS Standard C13 and N15-labeled recombinant protein (NP_236914) | 10 ug |
$3,360.00
|
|
| LC403251 | Lyophilized PDE5A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC421205 | Lyophilized PDE5A HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY403251 | Transient overexpression lysate of phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 2 (as WB positive control) | 100 ug |
$665.00
|
|
| LY421205 | Transient overexpression lysate of phosphodiesterase 5A, cGMP-specific (PDE5A), transcript variant 1 (as WB positive control) | 100 ug |
$665.00
|
|
Citations
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