CAMK2G (NM_172173) Human Recombinant Protein
SKU
TP317059
Recombinant protein of human calcium/calmodulin-dependent protein kinase II gamma (CAMK2G), transcript variant 6, 20 µg
$867.00
4 Weeks*
Specifications
| Product Data | |
| Species | Human |
|---|---|
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | |
| Tag | C-Myc/DDK |
| Predicted MW | 56.8 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Shipping | Dry Ice |
| Reference Data | |
| RefSeq | NP_751913 |
| Locus ID | 818 |
| UniProt ID | Q13555 |
| Cytogenetics | 10q22.2 |
| RefSeq Size | 3665 |
| RefSeq ORF | 1512 |
| Synonyms | CAMK; CAMK-II; CAMKG; MRD59 |
| Summary | The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.provided by RefSeq, Mar 2011 |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Calcium signaling pathway, ErbB signaling pathway, Glioma, GnRH signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Wnt signaling pathway |
Reviews
Documents
| FAQs |
| SDS |
Resources
| Recombinant Protein Resources |
Other "CAMK2G" proteins (8)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| PH317059 | CAMK2G MS Standard C13 and N15-labeled recombinant protein (NP_751913) | 10 ug |
$3,360.00
|
|
| LC406780 | Lyophilized CAMK2G HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC406781 | Lyophilized CAMK2G HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LC420064 | Lyophilized CAMK2G HEK293T cell transient overexpression lysate (as WB positive control) | 20 ug |
$206.00
|
|
| LY406780 | Transient overexpression lysate of calcium/calmodulin-dependent protein kinase II gamma (CAMK2G), transcript variant 2 (as WB positive control) | 100 ug |
$436.00
|
|
| LY406781 | Transient overexpression lysate of calcium/calmodulin-dependent protein kinase II gamma (CAMK2G), transcript variant 3 (as WB positive control) | 100 ug |
$436.00
|
|
| LY420064 | Transient overexpression lysate of calcium/calmodulin-dependent protein kinase II gamma (CAMK2G), transcript variant 4 (as WB positive control) | 100 ug |
$665.00
|
|
| TP761314 | Purified recombinant protein of Human calcium/calmodulin-dependent protein kinase II gamma (CAMK2G), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug | 50 ug |
$270.00
|
|
Citations
Ruxolitinib inhibits CaMKII-γ to reverse bortezomib resistance in multiple myeloma
Liang, Liu, 旭山 et al
Commun Biol (2026)
Liang, Liu, 旭山 et al
Commun Biol (2026)
AI Summary: OriGene’s Human recombinant CaMKII-γ protein (Cat# TP317059L) was used to establish a high-throughput screening assay to identify inhibitors, enabling the discovery of ruxolitinib as a selective CaMKII-γ inhibitor that reverses bortezomib resistance in multiple myeloma.
Snippet: Human recombinant CaMKII-γ was purchased from OriGene (Cat# TP317059L) to test the inhibitory effects of FDA-approved drug library containing 2665 FDA-approved;To discover new inhibitors for CaMKII-γ, a high-throughput screening system was established based on the CaMKII-γ kinase activity using 384-well plates. Human recombinant CaMKII-γ was purchased from OriGene (Cat# TP317059L) to test the inhibitory effects of FDA-approved drug library containing 2665 FDA-approved drugs (Obtained from MedChemExpress)
Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ
Williams, Walton, Pinell et al
Sci Rep (2021) 11 (1), 13116 DOI: 10.1038/s41598-021-92426-2
Williams, Walton, Pinell et al
Sci Rep (2021) 11 (1), 13116 DOI: 10.1038/s41598-021-92426-2
Cited by 22
AI Summary: OriGene’s recombinant myc-tagged Camk2g isoforms were used in this study to validate the Camk2 gamma antibody, supporting the investigation of alternative splicing of CaMK2γ in ischemic heart injury.
Snippet: Recombinant myc-tagged Camk2g isoforms were purchased from Origene and used to validate Camk2 gamma antibody (Supplementary Fig. 1). Rbfox1 antibody data is shown in Supplementary Fig. 2. RNA isolation and real-time PCR
Showing 1-2 of 2 papers.
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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